Calcium is an essential dietary mineral. It is present mainly in skeleton, which provides structural support for the body. Calcium is also necessary for muscle contractions, nerve cell signalling, and blood clotting. Calcium deficiency is known to lead to osteoporosis and is very common, with an estimated 20% of the worldwide population being calcium deficient.
Phosphorus is the second most plentiful mineral in your body. The first is calcium. Your body needs phosphorus for many functions, such as filtering waste and repairing tissue and cells. Phosphorus also helps to keep your bones strong and healthy, manage how your body stores and uses energy, and to move your muscles.
When calcium and phosphorus are naturally present in the right ratio of approximately 2:1, they then form a crystalline structure called hydroxyapatite. Calcium hydroxyapatite from fish bone is considered the most bioavailable form of calcium.
Fish collagen is a complex structural protein that helps maintain the strength and flexibility of skin, ligaments, joints, bones, muscles, tendons, blood vessels, gums, eyes, nails and hair. Fish collagen is a Type One collagen, which is the most abundant collagen in the human body. Type One is best known for providing the foundation for beautiful skin, strong connective tissues and sturdy bones. Fish collagen has recently shown its ability to increase the body’s own natural collagen reproduction.
(Refer “Effects of fish collagen peptides on collagen post-translational modifications and mineralization in an osteoblastic culture system”, National Institute of Health September 2013).
VITAMIN D3 & VITAMIN K2 (MK-7)
Vitamin D3 helps with the absorption of calcium and phosphorus, and helps the calcium to form in the bone matrix.
Vitamin K2 helps to bind calcium to proper places like bone matrix.
Vitamin K2 activates the GLA protein, which inhibits the formation of calcium in arterial walls. Vitamin K2 also activates a protein called osteocalcin that is produced by osteoblast cells. Osteocalcin helps to take calcium from the blood circulation and bind it to the bone matrix. Osteocalcin influences bone mineralization through its ability to bind to the mineral component of bone, hydroxyapatite, which in turn makes the skeleton stronger and less susceptible to fracture.
(Refer “Proper Calcium Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health” Integrative Medicine February 2015).